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Article

Toxin-antitoxin systems in bacterial growth arrest and persistence.

Nature chemical biology - 1 Apr 2016

Page Rebecca, Peti Wolfgang

Abstract excerpt

Bacterial persister cells constitute a subpopulation of genetically identical, metabolically slow-growing cells that are highly tolerant of antibiotics and other environmental stresses. Recent studies have demonstrated that gene loci known as toxin-antitoxin (TA) modules play a central role in the persister state. Under normal growth conditions, antitoxins potently inhibit the activities of the toxins. In...

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PMID: 26991085
DOI: 10.1038/nchembio.2044

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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