Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The toxin-antitoxin system tisB-istR1: Expression, regulation, and biological role in persister phenotypes.

RNA biology - 1 Dec 2012

Wagner E Gerhart H, Unoson Cecilia

Abstract excerpt

Chromosomally encoded toxin-antitoxin (TA) systems are abundantly present in bacteria and archaea. They have become a hot topic in recent years, because-after many frustrating years of searching for biological functions-some are now known to play roles in persister formation. Persister cells represent a subset of a bacterial population that enters a dormant state and thus becomes refractory to the action of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bacterial Toxins
Share to Chromosomes, Bacterial
Share to Hydrophobic and Hydrophilic Interactions

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Ribosomes

Share to RNA, Antisense

Share to RNA, Bacterial

Share to RNA Stability

Share to SOS Response, Genetics

Source

Identifiers

PMID: 23093802
DOI: 10.4161/rna.22578

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The toxin-antitoxin system tisB-istR1: Expression, regulation, and biological role in persister phenotypes.PMID 23093802Read ↗

Toxin-antitoxin systems in bacterial growth arrest and persistence.Semantic proximity Read ↗

Type II Toxin-Antitoxin Systems: Evolution and Revolutions.Semantic proximity Read ↗

Targeting Type II Toxin–Antitoxin Systems as Antibacterial StrategiesSemantic proximity Read ↗

Isolation of highly persistent mutants of Salmonella enterica serovar typhimurium reveals a new toxin-antitoxin module.Semantic proximity Read ↗

Linking toxin-antitoxin systems with phenotypes: A Staphylococcus aureus viewpoint.Semantic proximity Read ↗

Molecular mechanisms of multiple toxin-antitoxin systems are coordinated to govern the persister phenotype.Semantic proximity Read ↗

Integrative biology of persister cell formation: molecular circuitry, phenotypic diversification and fitness effects.Semantic proximity Read ↗

Multiple Toxin-Antitoxin Systems in Mycobacterium tuberculosisSemantic proximity Read ↗

Bacterial persistence from a system-level perspective.Semantic proximity Read ↗

Toxin-Antitoxin Genes of the Gram-Positive Pathogen Streptococcus pneumoniae: So Few and Yet So ManySemantic proximity Read ↗

Proteolytically Coordinated Activation of Toxin-Antitoxin ModulesSemantic proximity Read ↗

Divergently overlapping cis-encoded antisense RNA regulating toxin-antitoxin systems from E. coli: hok/sok, ldr/rdl, symE/symR.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.