Article
Persistence of obligate intracellular pathogens: alternative strategies to overcome host-specific stresses.
Frontiers in cellular and infection microbiology - 1 Jan 2023
Riffaud Camille M, Rucks Elizabeth A, Ouellette Scot P
Abstract excerpt
In adapting to the intracellular niche, obligate intracellular bacteria usually undergo a reduction of genome size by eliminating genes not needed for intracellular survival. These losses can include, for example, genes involved in nutrient anabolic pathways or in stress response. Living inside a host cell offers a stable environment where intracellular bacteria can limit their exposure to extracellular effectors...
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