Article
Surfactant protein-C chromatin-bound green fluorescence protein reporter mice reveal heterogeneity of surfactant protein C-expressing lung cells.
American journal of respiratory cell and molecular biology - 1 Mar 2013
Lee Joo-Hyeon, Kim Jonghwan, Gludish David, Roach Rebecca R, Saunders Arven H, Barrios Juliana, Woo Andrew Jonghan, Chen Huaiyong, Conner David A, Fujiwara Yuko, Stripp Barry R, Kim Carla F
Abstract excerpt
The regeneration of alveolar epithelial cells is a critical aspect of alveolar reorganization after lung injury. Although alveolar Type II (AT2) cells have been described as progenitor cells for alveolar epithelia, more remains to be understood about how their progenitor cell properties are regulated. A nuclear, chromatin-bound green fluorescence protein reporter (H2B-GFP) was driven from the murine surfactant...
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