Article

GRAMD2 <sup>+</sup> alveolar type I cell plasticity facilitates cell state transitions in organoid culture

2023-10-18

Abstract excerpt

<h4>SUMMARY</h4> Alveolar epithelial regeneration is critical for normal lung function and becomes dysregulated in disease. While alveolar type 2 (AT2) and club cells are known distal lung epithelial progenitors, determining if alveolar epithelial type 1 (AT1) cells also contribute to alveolar regeneration has been hampered by lack of highly specific mouse models labeling AT1 cells. To address this, the Gramd2...

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Literature Corpus work: 2d4cfa2d-d9ed-5365-a3bf-8f7928b04d8c
DOI: 10.1101/2023.10.17.560801

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