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Article

Generation and characterization of pilocarpine-sensitive C57BL/6 mice as a model of temporal lobe epilepsy.

Behavioural brain research - 21 Apr 2012

Bankstahl Marion, Müller Christine J, Wilk Esther, Schughart Klaus, Löscher Wolfgang

Abstract excerpt

C57BL/6 (B6) is the most widely used inbred mouse strain, but its use in epilepsy research is compromised by low sensitivity to various convulsants, including pilocarpine. We recently identified a subline of B6NCrl mice in a barrier (#8) of a German vendor (Charles River) that was much more sensitive to status epilepticus (SE) induction than B6NCrl mice from four other barriers of the same vendor and other B6...

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Source

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PMID: 22348894
DOI: 10.1016/j.bbr.2012.02.004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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