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Article

Experimental models of multifactorial epilepsies: the EL mouse and mice susceptible to audiogenic seizures.

Advances in neurology - 1 Jan 1999

Seyfried T N, Todorova M T, Poderycki M J

Abstract excerpt

This chapter reviews two well-characterized mouse epilepsy models with a multifactorial etiology, the epileptic EL mouse and mice susceptible to audiogenic seizures (AGS). Multifactorial disorders are quantitative traits where the action of more than one gene together with environmental factors contributes to the disease phenotype. The EL (epilepsy) mouse has been studied extensively as a genetic model for...

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PMID: 10514820

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