Association of type 2 diabetes susceptibility variants with advanced prostate cancer risk in the Breast and Prostate Cancer Cohort Consortium.

doi:10.1093/aje/kws191

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Article

Association of type 2 diabetes susceptibility variants with advanced prostate cancer risk in the Breast and Prostate Cancer Cohort Consortium.

American journal of epidemiology - 15 Dec 2012

Machiela Mitchell J, Lindström Sara, Allen Naomi E, Haiman Christopher A, Albanes Demetrius, Barricarte Aurelio, Berndt Sonja I, Bueno-de-Mesquita H Bas, Chanock Stephen, Gaziano J Michael, Gapstur Susan M, Giovannucci Edward, Henderson Brian E, Jacobs Eric J, Kolonel Laurence N, Krogh Vittorio, Ma Jing, Stampfer Meir J, Stevens Victoria L, Stram Daniel O, Tjønneland Anne, Travis Ruth, Willett Walter C, Hunter David J, Le Marchand Loic, Kraft Peter

Abstract excerpt

Observational studies have found an inverse association between type 2 diabetes (T2D) and prostate cancer (PCa), and genome-wide association studies have found common variants near 3 loci associated with both diseases. The authors examined whether a genetic background that favors T2D is associated with risk of advanced PCa. Data from the National Cancer Institute's Breast and Prostate Cancer Cohort Consortium, a...

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PMID: 23193118
DOI: 10.1093/aje/kws191
PMCID: PMC3571230

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ADCY5
FTO
JAZF1
KCNQ1
NOTCH2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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