Article
Computational analyses of type 2 diabetes-associated loci identified by genome-wide association studies.
Journal of diabetes - 1 Apr 2017
Cheng Mengrong, Liu Xinhong, Yang Mei, Han Lanchun, Xu Aimin, Huang Qingyang
Abstract excerpt
BACKGROUND: Genome-wide association studies (GWAS) of type 2 diabetes (T2D) have discovered a number of loci that contribute to susceptibility to the disease. Future challenges include elucidation of functional mechanisms through which these GWAS-identified loci modulate T2D disease risk. The aim of the present study was to comprehensively characterize T2D associated single nucleotide polymorphisms (SNPs) and...
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