Article
Genetic susceptibility to type 2 diabetes is associated with reduced prostate cancer risk.
Human heredity - 1 Jan 2010
Pierce Brandon L, Ahsan Habibul
Abstract excerpt
OBJECTIVE: To examine the collective effects of type 1 (T1D) and type 2 diabetes (T2D) risk alleles on prostate cancer (PCa) risk. METHODS: Using data on 14 and 18 single nucleotide polymorphisms (SNPs) that effect T1D and T2D risk, respectively, we generated risk scores (a 'risk allele count' and a 'genetic relative risk') for both T1D and T2D for 1,171 non-Hispanic white, PSA-screened PCa cases and 1,101...
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