Article
An assessment of the shared allelic architecture between type II diabetes and prostate cancer.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Aug 2013
Yu Oriana Hoi Yun, Foulkes William D, Dastani Zari, Martin Richard M, Eeles Rosalind, Richards J Brent
Abstract excerpt
BACKGROUND: To determine whether the alleles that influence type II diabetes risk and glycemic traits also influence prostate cancer risk. METHODS: We used a multiple single-nucleotide polymorphisms (SNP) genotypic risk score to assess the average effect of alleles that increase type II diabetes risk or worsen glycemic traits on risk of prostate cancer in 19,662 prostate cancer cases and 19,715 controls from the...
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