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No association of type 2 diabetes risk variants and prostate cancer risk: the multiethnic cohort and PAGE.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Sept 2011

Waters Kevin M, Wilkens Lynne R, Monroe Kristine R, Stram Daniel O, Kolonel Laurence N, Henderson Brian E, Le Marchand Loïc, Haiman Christopher A

Abstract excerpt

BACKGROUND: Epidemiologic studies have found evidence of an inverse association between diabetes status and prostate cancer risk. We explored the hypothesis that common genetic variation may explain, in part, the inverse association between diabetes and prostate cancer. METHODS: We tested 17 diabetes risk variants for association with prostate cancer risk in a prostate cancer case-control study of 2,746 cases and...

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PMID: 21750171
DOI: 10.1158/1055-9965.EPI-11-0019
PMCID: PMC3175821

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