Article
Evaluation of a variant in the transcription factor 7-like 2 (TCF7L2) gene and prostate cancer risk in a population-based study.
The Prostate - 15 May 2008
Agalliu Ilir, Suuriniemi Miia, Prokunina-Olsson Ludmila, Johanneson Bo, Collins Francis S, Stanford Janet L, Ostrander Elaine A
Abstract excerpt
BACKGROUND: Transcription factor 7-like 2 (TCF7L2) is a high mobility group-box containing protein that is a critical member of the Wnt/beta-catenin canonical signaling pathway. In addition to its recently recognized role in diabetes, aberrant TCF7L2 expression has been implicated in cancer throu...
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