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Article

Risk prediction for sporadic Alzheimer's disease using genetic risk score in the Han Chinese population.

Oncotarget - 10 Nov 2015

Xiao Qianyi, Liu Zhi-Jun, Tao Sha, Sun Yi-Min, Jiang Deke, Li Hong-Lei, Chen Haitao, Liu Xu, Lapin Brittany, Wang Chi-Hsiung, Zheng S Lilly, Xu Jianfeng, Wu Zhi-Ying

Abstract excerpt

More than 30 independent single-nucleotide polymorphisms (SNPs) have been associated with Alzheimer's disease (AD) risk by genome-wide association studies (GWAS) in European. We aimed to confirm these SNPs in Chinese Han and investigate the utility of these genetic markers. We randomly divided 459 sporadic AD (SAD) patients and 751 cognitively normal controls into two sets (discovery and testing). Thirty-three...

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Source

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Identifiers

PMID: 26543236
DOI: 10.18632/oncotarget.6271
PMCID: PMC4741908

Genes

APOE
FERMT2
SORL1
TOMM40

Provenance

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