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Genetic association between low-density lipoprotein receptor-related protein gene polymorphisms and Alzheimer's disease in Chinese Han population.

Neuroscience letters - 17 Oct 2008

Zhou Yong-Tao, Zhang Zhen-Xin, Chan Piu, He Xiao-Ming, Tang Mou-Ni, Wu Cheng-Bin, Hong Zhen

Abstract excerpt

Alzheimer's disease (AD) is the most common neurodegenerative disorders in the elderly. Low-density lipoprotein receptor-related protein (LRP), as a receptor of apolipoprotein E (APOE), APP, and alpha2 macroglobulin (alpha2-M), keeps the balance between degeneration and production of beta-amyloid protein (Abeta) clearance. Its gene had been defined as a candidate gene for AD, but the results were not universal....

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Source

Identifiers

PMID: 18706476
DOI: 10.1016/j.neulet.2008.07.093

Genes

APOE
APP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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