A single nucleotide polymorphism in LRP2 is associated with susceptibility to Alzheimer's disease in the Chinese population.

doi:10.1016/j.cca.2010.10.015

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

A single nucleotide polymorphism in LRP2 is associated with susceptibility to Alzheimer's disease in the Chinese population.

Clinica chimica acta; international journal of clinical chemistry - 30 Jan 2011

Wang Li-Ling, Pan Xiao-Ling, Wang Ying, Tang Hui-Dong, Deng Yu-Lei, Ren Ru-Jing, Xu Wei, Ma Jian-Fang, Wang Gang, Chen Sheng-Di

Abstract excerpt

BACKGROUND: LRP2 (also called megalin) plays a potential key role in the pathogenesis of Alzheimer's disease (AD). Recently, one genome-wide association study has revealed that the rs3755166 (G/A) polymorphism located in the LRP2 promoter is associated with development of AD in Caucasians, while there are no studies on the association LRP2 of with AD risk in Asians. METHODS: To evaluate the relationship between...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Alzheimer Disease

Share to Apolipoproteins E

Share to Asian People

Share to Case-Control Studies

Share to China

Share to Gene Frequency

Share to Low Density Lipoprotein Receptor-Related Protein-2

Source

Open in PubMed

Identifiers

PMID: 20971101
DOI: 10.1016/j.cca.2010.10.015

Genes

LRP2
APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A single nucleotide polymorphism in LRP2 is associated with susceptibility to Alzheimer's disease in the Chinese population.PMID 20971101Read ↗

Genetic association between low-density lipoprotein receptor-related protein gene polymorphisms and Alzheimer's disease in Chinese Han population.Semantic proximity Read ↗

Meta-analyses of 8 polymorphisms associated with the risk of the Alzheimer's disease.Semantic proximity Read ↗

Association between LRP1 C766T polymorphism and Alzheimer's disease susceptibility: a meta-analysis.Semantic proximity Read ↗

CLU rs2279590 polymorphism contributes to Alzheimer's disease susceptibility in Caucasian and Asian populations.Semantic proximity Read ↗

Whole-genome sequencing reveals novel ethnicity-specific rare variants associated with Alzheimer's disease.Semantic proximity Read ↗

Association study of the A2M and LRP1 Genes with Alzheimer disease in the Han Chinese.Semantic proximity Read ↗

Rare, pathogenic variants in LRP10 are associated with amyotrophic lateral sclerosis in patients from mainland China.Semantic proximity Read ↗

Risk prediction for sporadic Alzheimer's disease using genetic risk score in the Han Chinese population.Semantic proximity Read ↗

Genetic association of CUGBP2 and DNMBP with Alzheimer' s disease in the Chinese Han population.Semantic proximity Read ↗

The LRRK2 R1628P variant plays a protective role in Han Chinese population with Alzheimer's disease.Semantic proximity Read ↗

Association of polymorphisms in the LRP1 and A2M genes with Alzheimer's disease in the northern Chinese Han population.Semantic proximity Read ↗

Correlation of PICALM polymorphism rs3851179 with Alzheimer's disease among Caucasian and Chinese populations: a meta-analysis and systematic review.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.