Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic variants of SNCA and LRRK2 genes are associated with sporadic PD susceptibility: a replication study in a Taiwanese cohort.

Parkinsonism & related disorders - 1 Feb 2013

Wu-Chou Yah-Huei, Chen Ying-Ting, Yeh Tu-Hsueh, Chang Hsiu-Chen, Weng Yi-Hsin, Lai Szu-Chia, Huang Chia-Ling, Chen Rou-Shayn, Huang Ying-Zu, Chen Chiung-Chu, Hung June, Chuang Wen-Li, Lin Wey-Yil, Chen Chien-Hsiun, Lu Chin-Song

Abstract excerpt

BACKGROUND: Parkinson's disease (PD) is one of the most prevalent age-related neurodegenerative diseases and usually refers to a complex disorder with multiple genetic and environmental factors influencing disease risk. We here performed a gene-based case-control association study to scrutinize whether genetic variants in SNCA and LRRK2 genes could predispose to sporadic, late-onset form of PD in Taiwanese...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to alpha-Synuclein

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Case-Control Studies

Share to Leucine-Rich Repeat Serine-Threonine Protein Kinase-2

Share to Parkinson Disease

Share to Polymorphism, Single Nucleotide

Share to Protein Serine-Threonine Kinases

Share to Taiwan

Source

Identifiers

PMID: 23182315
DOI: 10.1016/j.parkreldis.2012.10.019

Genes

SNCA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic variants of SNCA and LRRK2 genes are associated with sporadic PD susceptibility: a replication study in a Taiwanese cohort.PMID 23182315Read ↗

Genetic variants ofLRRK2 in Taiwanese Parkinson's disease.Semantic proximity Read ↗

LRRK2 mutations and risk variants in Japanese patients with Parkinson's disease.Semantic proximity Read ↗

SNCA rs356182 variant increases risk of sporadic Parkinson's disease in ethnic Chinese.Semantic proximity Read ↗

SNCA polymorphisms, smoking, and sporadic Parkinson's disease in Japanese.Semantic proximity Read ↗

Association between SNCA rs2736990 polymorphism and Parkinson's disease: a meta-analysis.Semantic proximity Read ↗

Genome-wide association study reveals genetic risk underlying Parkinson's disease.Semantic proximity Read ↗

Genome-wide association study identifies common variants at four loci as genetic risk factors for Parkinson's disease.Semantic proximity Read ↗

The association between the LRRK2 G2385R variant and the risk of Parkinson's disease: a meta-analysis based on 23 case-control studies.Semantic proximity Read ↗

Leucine-Rich Repeat Kinase (LRRK2) Genetics and Parkinson's Disease.Semantic proximity Read ↗

Genetic analysis of LRRK2 in Parkinson's disease in Han Chinese population.Semantic proximity Read ↗

Association between SNCA Intron and genetic predisposition to sporadic Parkinson's disease: a meta-analysis based on 49576 individualsSemantic proximity Read ↗

Penetrance of LRRK2 G2385R and R1628P is modified by common PD-associated genetic variants.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.