NGL-2 regulates input-specific synapse development in CA1 pyramidal neurons.

Abstract excerpt

An important organizing feature of the CNS is that individual neurons receive input from many different sources. Independent regulation of synaptic input is critical for the function and adaptive responses of the nervous system, but the underlying molecular mechanisms are not well understood. We identify the leucine-rich repeat (LRR)-containing protein NGL-2 (Lrrc4) as a key regulator of input-specific synapse...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to CA1 Region, Hippocampal
• Share to Excitatory Amino Acid Agonists
• Share to Excitatory Postsynaptic Potentials