Article

Distinct nanoscale architectures of GABAergic inhibitory synapses predict diverse synaptic output

2026-06-28

Abstract excerpt

<h4>ABSTRACT</h4> GABAergic synaptic inhibition is heterogenous across neuronal compartments, and plays a critical role in shaping local, cellular and circuit excitability. In pyramidal neurons, inhibition is mediated by GABA A receptors (GABA A Rs) clustered at the inhibitory postsynaptic domain (iPSD). Synaptic strength depends not only on the number of GABA A Rs within the iPSD, but also on their precise na...

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Literature Corpus work: 10a14a9b-a151-535f-987b-b75081a0efa6
DOI: 10.64898/2026.06.26.734878

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