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Article

Reduced mitochondrial DNA copy number in Chinese patients with osteosarcoma.

Translational research : the journal of laboratory and clinical medicine - 1 Mar 2013

Yu Man, Wan Yanfang, Zou Qinghua

Abstract excerpt

A plethora of somatic mutations and germline variations in mitochondrial DNA (mtDNA) have been increasingly reported in numerous cancer entities including osteosarcoma. However, it remains largely unclear whether mtDNA copy number changes occur during the multistep process of osteosarcoma carcinogenesis. For this purpose, we determined quantitative mtDNA levels in 31 primary osteosarcoma specimens and 5 normal...

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Identifiers

PMID: 23177796
DOI: 10.1016/j.trsl.2012.10.011

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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