Article
RIM controls homeostatic plasticity through modulation of the readily-releasable vesicle pool.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 21 Nov 2012
Müller Martin, Liu Karen Suk Yin, Sigrist Stephan J, Davis Graeme W
Abstract excerpt
Rab3 interacting molecules (RIMs) are evolutionarily conserved scaffolding proteins that are located at presynaptic active zones. In the mammalian nervous system, RIMs have two major activities that contribute to the fidelity of baseline synaptic transmission: they concentrate calcium channels at the active zone and facilitate synaptic vesicle docking/priming. Here we confirm that RIM has an evolutionarily...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
