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Article

Direct interactions between C. elegans RAB-3 and Rim provide a mechanism to target vesicles to the presynaptic density.

Neuroscience letters - 24 Oct 2008

Gracheva Elena O, Hadwiger Gayla, Nonet Michael L, Richmond Janet E

Abstract excerpt

Rim is a multi-domain, active zone protein that regulates exocytosis and is implicated in vesicle priming and presynaptic plasticity. We recently demonstrated that synaptic defects associated with loss of Caenorhabditis elegans Rim (termed UNC-10) are accompanied by a reduction in docked vesicles adjacent to the presynaptic density. Since Rim is known to interact with the vesicle-associated GTPase Rab3A, here we...

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Identifiers

PMID: 18721860
DOI: 10.1016/j.neulet.2008.08.026
PMCID: PMC2585374

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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