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Article

Influence of a nucleotide oligomerization domain 1 (NOD1) polymorphism and NOD2 mutant alleles on Crohn's disease phenotype.

World journal of gastroenterology - 7 Nov 2007

Cantó Elisabet, Ricart Elena, Busquets David, Monfort David, García-Planella Esther, González Dolors, Balanzó Joaquim, Rodriguez-Sanchez José-L, Vidal Sílvia

Abstract excerpt

AIM: To examine genetic variation of nucleotide oligomerization domain 1 (NOD1) and NOD2, their respective influences on Crohn's disease phenotype and gene-gene interactions. METHODS: (ND(1)+32656*) NOD1 polymorphism and SNP8, SNP12 and SNP13 of NOD2 were analyzed in 97 patients and 50 controls. NOD2 variants were determined by reaction restriction fragment length polymorphism analysis. NOD1 genotyping and NOD2...

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Case-Control Studies
Colon
Crohn Disease
Ileum
Nod1 Signaling Adaptor Protein

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Nod2 Signaling Adaptor Protein

Polymorphism, Restriction Fragment Length

Severity of Illness Index

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Identifiers

PMID: 17907287
DOI: 10.3748/wjg.v13.i41.5446
PMCID: PMC4171278

Genes

NOD2
NOD1

Variants

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