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Article

The effect of NOD2 on the microbiota in Crohn's disease.

Current opinion in biotechnology - 1 Aug 2016

Lauro Mackenzie L, Burch Jason M, Grimes Catherine Leimkuhler

Abstract excerpt

Recent advancements toward the treatment of Crohn's disease (CD) indicate great promise for long-term remission. CD patients suffer from a complex host of dysregulated interactions between their innate immune system and microbiome. The most predominant link to the onset of CD is a genetic mutation in the innate immune receptor nucleotide-binding oligomerization domain-containing 2 (NOD2). NOD2 responds to the...

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Source

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Identifiers

PMID: 27035071
DOI: 10.1016/j.copbio.2016.02.028
PMCID: PMC5820027

Genes

NOD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

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