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Article

Functional crosstalk in culture between macrophages and trigeminal sensory neurons of a mouse genetic model of migraine.

BMC neuroscience - 21 Nov 2012

Franceschini Alessia, Nair Asha, Bele Tanja, van den Maagdenberg Arn Mjm, Nistri Andrea, Fabbretti Elsa

Abstract excerpt

BACKGROUND: Enhanced activity of trigeminal ganglion neurons is thought to underlie neuronal sensitization facilitating the onset of chronic pain attacks, including migraine. Recurrent headache attacks might establish a chronic neuroinflammatory ganglion profile contributing to the hypersensitive phenotype. Since it is difficult to study this process in vivo, we investigated functional crosstalk between...

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Identifiers

PMID: 23171280
DOI: 10.1186/1471-2202-13-143
PMCID: PMC3511260

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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