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Article

TNFα levels and macrophages expression reflect an inflammatory potential of trigeminal ganglia in a mouse model of familial hemiplegic migraine.

PloS one - 1 Jan 2013

Franceschini Alessia, Vilotti Sandra, Ferrari Michel D, van den Maagdenberg Arn M J M, Nistri Andrea, Fabbretti Elsa

Abstract excerpt

Latent changes in trigeminal ganglion structure and function resembling inflammatory conditions may predispose to acute attacks of migraine pain. Here, we investigated whether, in trigeminal sensory ganglia, cytokines such as TNFα might contribute to a local inflammatory phenotype of a transgenic knock-in (KI) mouse model of familial hemiplegic migraine type-1 (FHM-1). To this end, macrophage occurrence and...

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Identifiers

PMID: 23326332
DOI: 10.1371/journal.pone.0052394
PMCID: PMC3543418

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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