Article
Association of paraoxonase1 gene Q192R polymorphism and apolipoprotein B in Asian Indian women with coronary artery disease risk.
Genetic testing and molecular biomarkers - 1 Feb 2013
Deshpande Chetana S, Singhal Rekha S, Mukherjee Manjari S
Abstract excerpt
BACKGROUND/AIMS: Human serum paraoxonase1 (PON1), a high-density lipoprotein-associated enzyme, prevents oxidative modification of low-density lipoprotein and, thus, arrests the development of atheroma formation, whose major consequence is the development of coronary artery disease (CAD). A single-nucleotide polymorphism (SNP) Q192R in the coding region at pon1 locus is a determinant of PON1 activity. The...
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