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Article

Paraoxonase-1 (PON1) activity, but not PON1(Q192R) phenotype, is a predictor of coronary artery disease in a middle-aged Serbian population.

Clinical chemistry and laboratory medicine - 1 Jan 2006

Kotur-Stevuljevic Jelena, Spasic Slavica, Stefanovic Aleksandra, Zeljkovic Aleksandra, Bogavac-Stanojevic Natasa, Kalimanovska-Ostric Dimitra, Spasojevic-Kalimanovska Vesna, Jelic-Ivanovic Zorana

Abstract excerpt

BACKGROUND: Paraoxonase-1 (PON1) is a high-density lipoprotein (HDL)-associated serum enzyme that protects lipoproteins from oxidative modifications. Polymorphisms in the gene, including PON1Q192R, have been studied. However, inconsistencies regarding the above-mentioned polymorphism obscure its association with vascular disease. METHODS: Using a two-substrate (paraoxon/diazoxon) activity method, we investigated...

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Source

Identifiers

PMID: 17032132
DOI: 10.1515/CCLM.2006.216

Genes

PON1
CAD

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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