Article
Paraoxonase gene polymorphism and coronary artery disease in Indian subjects.
International journal of cardiology - 30 Sept 1998
Pati N, Pati U
Abstract excerpt
The human serum HDL-linked paraoxonase enzyme limits the LDL peroxidation by preventing transformation of LDL into biologically active atherogenic particles. Paraoxonase serum activity varies among individuals due to an Gln/Arg polymorphism with low (A phenotype) and high activity (B phenotype)....
Topics
- Aged
- Aryldialkylphosphatase
- Coronary Disease
- Esterases
- Humans
- India
- Middle Aged
- Phenotype
- Polymorphism, Genetic
- Polymorphism, Restriction Fragment Length