Association of VEGF and KDR single nucleotide polymorphisms with colorectal cancer susceptibility in Koreans.

doi:10.1002/mc.21980

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Article

Association of VEGF and KDR single nucleotide polymorphisms with colorectal cancer susceptibility in Koreans.

Molecular carcinogenesis - 1 Nov 2013

Jang Moon Ju, Jeon Young Joo, Kim Jong Woo, Cho Yun Kyung, Lee Seung Ku, Hwang Seong Gyu, Oh Doyeun, Kim Nam Keun

Abstract excerpt

Vascular endothelial growth factor (VEGF) and its receptor kinase insert domain-containing receptor (KDR) play crucial roles in angiogenesis, which contributes to the development and progression of solid tumors. The aim of this study was to investigate the associations of VEGF (-2578C > A, -1154G...

Topics

Biomarkers, Tumor
Case-Control Studies
Colorectal Neoplasms
Female
Gene-Environment Interaction
Genetic Predisposition to Disease
Genotype
Humans
Male
Middle Aged
Neoplasm Staging

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymerase Chain Reaction

Polymorphism, Single Nucleotide

Prognosis

Republic of Korea

Risk Factors

Vascular Endothelial Growth Factor A

Vascular Endothelial Growth Factor Receptor-2

Source

Open in PubMed

Identifiers

PMID: 23169005
DOI: 10.1002/mc.21980

Genes

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-23169005-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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