Article
Association of VEGF and KDR single nucleotide polymorphisms with colorectal cancer susceptibility in Koreans.
Molecular carcinogenesis - 1 Nov 2013
Jang Moon Ju, Jeon Young Joo, Kim Jong Woo, Cho Yun Kyung, Lee Seung Ku, Hwang Seong Gyu, Oh Doyeun, Kim Nam Keun
Abstract excerpt
Vascular endothelial growth factor (VEGF) and its receptor kinase insert domain-containing receptor (KDR) play crucial roles in angiogenesis, which contributes to the development and progression of solid tumors. The aim of this study was to investigate the associations of VEGF (-2578C > A, -1154G > A, -634G > C, and 936C > T) and KDR (-604T > C and 1192G > A) polymorphisms with the development of colorectal...
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