Article
VEGF polymorphisms may be associated with susceptibility to colorectal cancer: a case-control study.
Cancer biomarkers : section A of Disease markers - 1 Jan 2011
Antonacopoulou Anna G, Kottorou Anastasia E, Dimitrakopoulos Fotinos-Ioannis D, Triantafyllia Vasiliki, Marousi Stella, Koutras Angelos, Kalofonos Haralabos P
Abstract excerpt
The vascular endothelial growth factor (VEGF) has a pivotal role in angiogenesis. VEGF levels appear to be influenced by single nucleotide polymorphisms (SNPs) of the VEGF gene. The aim of this study was to assess the importance of four VEGF SNPs in modulating susceptibility to colorectal cancer. We have genotyped 223 patients with colorectal cancer and 264 healthy individuals for the -2578C>A, -1498C>T, -634G>C...
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