Article
Association of vascular endothelial growth factor gene polymorphisms with susceptibility and clinicopathologic characteristics of colorectal cancer.
Journal of Korean medical science - 1 Jun 2008
Chae Yee Soo, Kim Jong Gwang, Sohn Sang Kyun, Cho Yoon Young, Ahn Byung Min, Moon Joon Ho, Jeon Seoung Woo, Park Jae Yong, Lee In Taek, Choi Gyu Seog, Jun Soo-Han
Abstract excerpt
Since vascular endothelial growth factor (VEGF) is known to be a potent pro-angiogenic factor, we evaluated the potential association of two VEGF gene polymorphisms (-634G>C and 936C>T) with the susceptibility and the clinicopathologic characteristics of colorectal cancer (CRC). The VEGF genotypes were determined using fresh colorectal tissue from 465 patients who had undergone a surgical resection and peripheral...
Topics
- Adult
- Aged
- Aged, 80 and over
- Colorectal Neoplasms
- Female
- Genetic Predisposition to Disease
- Haplotypes
- Humans
- Male
- Middle Aged
