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Article

Common polymorphisms in the vascular endothelial growth factor gene and colorectal cancer development, prognosis, and survival.

Molecular carcinogenesis - 1 Jun 2009

Dassoulas Konstantinos, Gazouli Maria, Rizos Spyros, Theodoropoulos George, Christoni Zoi, Nikiteas Nikolaos, Karakitsos Petros

Abstract excerpt

Angiogenesis plays an important role in growth, progression, and metastasis of tumors. The most important regulator of angiogenesis is vascular endothelial growth factor (VEGF). VEGF expression has been associated with advance stage and poor survival of several cancers. In the present study we evaluated the association of functional polymorphisms in the VEGF gene with colorectal cancer development, prognosis, and...

Topics

Alleles
Case-Control Studies
Colorectal Neoplasms
Gene Frequency
Paraffin Embedding
Polymerase Chain Reaction
Polymorphism, Restriction Fragment Length
Polymorphism, Single Nucleotide
Prognosis
Survival Analysis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Vascular Endothelial Growth Factor A

Source

Identifiers

PMID: 19009560
DOI: 10.1002/mc.20495

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-19009560-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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