Vascular endothelial growth factor 1498C/T, 936C/T polymorphisms associated with increased risk of colorectal adenoma: a Chinese case-control study.

doi:10.1007/s11033-010-0316-7

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Article

Vascular endothelial growth factor 1498C/T, 936C/T polymorphisms associated with increased risk of colorectal adenoma: a Chinese case-control study.

Molecular biology reports - 1 Mar 2011

Wu Xianglei, Li Dongqing, Liu Zhisu, Wan Xinyue, Wu Yunhua, Jiang Congqin, Qian Qun

Abstract excerpt

Single nucleotide polymorphisms in vascular endothelial growth factor gene VEGF, 1498C/T and 936 C/T are associated with colorectal cancer. We sought to determine whether such genetic variability in VEGF contributes to susceptibility of colorectal adenoma (CRA), a presumably precancerous state of colorectal cancer. In this research, two aforementioned polymorphisms were investigated for CRA susceptibility in a...

Topics

Adenoma
Adolescent
Adult
Aged
Asian People
Case-Control Studies
China
Colorectal Neoplasms
Female
Genetic Predisposition to Disease
Haplotypes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Humans

Male

Middle Aged

Polymorphism, Single Nucleotide

Risk Factors

Vascular Endothelial Growth Factor A

Young Adult

Source

Open in PubMed

Identifiers

PMID: 20857215
DOI: 10.1007/s11033-010-0316-7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-20857215-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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