Article
A microRNA binding site polymorphism in the 3' UTR region of VEGF-A gene modifies colorectal cancer risk based on ethnicity: a meta-analysis.
Journal of the Egyptian National Cancer Institute - 25 Apr 2022
Kontham Sai Sushmitha, Walter Charles Emmanuel Jebaraj, Shankaran Zioni Sangeetha, Ramanathan Arvind, Karuppasamy Nirmala, Johnson Thanka
Abstract excerpt
BACKGROUND: Vascular endothelial growth factor A (VEGF-A) plays an integral role in angiogenesis by contributing to growth, development, and metastasis of solid tumors. Recently, a single-nucleotide polymorphism +936C/T located in the VEGF-A 3' untranslated region (UTR) facilitated the susceptibility of colorectal cancer. The association between VEGF-A gene polymorphism +936C/T and colorectal cancer risk has been...
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