Article
Association of VEGF genotype with mRNA level in colorectal adenocarcinomas.
Biochemical and biophysical research communications - 3 Dec 2004
Yamamori Motohiro, Sakaeda Toshiyuki, Nakamura Tsutomu, Okamura Noboru, Tamura Takao, Aoyama Nobuo, Kamigaki Takashi, Ohno Masakazu, Shirakawa Toshiro, Gotoh Akinobu, Kuroda Yoshikazu, Matsuo Masafumi, Kasuga Masato, Okumura Katsuhiko
Abstract excerpt
The mRNA expression of vascular endothelial growth factor (VEGF) was evaluated in colorectal adenocarcinomas and adjacent noncancerous colorectal tissues in 18 Japanese patients. The expression was confirmed to be up-regulated in the colorectal adenocarcinomas, when compared with the noncancerous tissues. Twelve genotypes of VEGF: six positions in the promoter region, two in the 5'UTR, and four in the 3'UTR, and...
Topics
- Adenocarcinoma
- Base Sequence
- Colorectal Neoplasms
- DNA Mutational Analysis
- Female
- Genotype
- Humans
- Japan
- Male
- Molecular Sequence Data