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Article

Gating of the designed trimeric/tetrameric voltage-gated H+ channel.

The Journal of physiology - 1 Feb 2013

Fujiwara Yuichiro, Kurokawa Tatsuki, Takeshita Kohei, Nakagawa Atsushi, Larsson H Peter, Okamura Yasushi

Abstract excerpt

The voltage-gated H(+) channel functions as a dimer, a configuration that is different from standard tetrameric voltage-gated channels. Each channel protomer has its own permeation pathway. The C-terminal coiled-coil domain has been shown to be necessary for both dimerization and cooperative gating in the two channel protomers. Here we report the gating cooperativity in trimeric and tetrameric Hv channels...

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Identifiers

PMID: 23165764
DOI: 10.1113/jphysiol.2012.243006
PMCID: PMC3577547

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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