Article
Oligomerization of the voltage-gated proton channel.
Channels (Austin, Tex.) - 1 Jan 2000
Musset Boris, Smith Susan M E, Rajan Sindhu, Cherny Vladimir V, Morgan Deri, DeCoursey Thomas E
Abstract excerpt
The voltage-gated proton channel exists as a dimer, although each protomer has a separate conduction pathway, and when forced to exist as a monomer, most major functions are retained. However, the proton channel protomers appear to interact during gating. Proton channel dimerization is thought to result mainly from coiled-coil interaction of the intracellular C-termini. Several types of evidence are discussed...
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