Article
Coupled tertiary folding and oligomerization of the T1 domain of Kv channels.
Neuron - 20 Jan 2005
Robinson John M, Deutsch Carol
Abstract excerpt
Acquisition of secondary, tertiary, and quaternary structure is critical to the fabrication, assembly, and function of ion channels, yet the relationship between these biogenic events remains unclear. We now address this issue in voltage-gated K(+) channels (Kv) for the T1 domain, an N-terminal Kv recognition domain that is responsible for subfamily-specific, efficient assembly of Kv subunits. This domain forms a...
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