Article
Structural insight into KCNQ (Kv7) channel assembly and channelopathy.
Neuron - 1 Mar 2007
Howard Rebecca J, Clark Kimberly A, Holton James M, Minor Daniel L
Abstract excerpt
Kv7.x (KCNQ) voltage-gated potassium channels form the cardiac and auditory I(Ks) current and the neuronal M-current. The five Kv7 subtypes have distinct assembly preferences encoded by a C-terminal cytoplasmic assembly domain, the A-domain Tail. Here, we present the high-resolution structure of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
