Article
Dysexecutive and amnesic AD subtypes defined by single indicator and modern psychometric approaches: relationships with SNPs in ADNI.
Brain imaging and behavior - 1 Dec 2012
Mukherjee Shubhabrata, Trittschuh Emily, Gibbons Laura E, Mackin R Scott, Saykin Andrew, Crane Paul K
Abstract excerpt
Previous investigators have suggested the existence of distinct cognitive phenotypes of Alzheimer's disease (AD): a dysexecutive subgroup with executive functioning worse than memory and an amnesic subgroup with memory worse than executive functioning. We evaluated data from the AD Neuroimaging Initiative. We assigned people with AD to dysexecutive and amnesic subgroups using single indicators, and analogously...
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