Article
[KRAS and BRAF gene mutations in correlation with clinicopathologic features of colorectal carcinoma in Chinese].
Zhonghua bing li xue za zhi = Chinese journal of pathology - 1 Sept 2012
Zhu Xiao-li, Cai Xu, Zhang Ling, Yang Fei, Sheng Wei-qi, Lu Yong-ming, Du Xiang, Zhou Xiao-yan
Abstract excerpt
OBJECTIVE: To retrospectively analyze KRAS and BRAF gene mutation features in Chinese colorectal cancer (CRC) and their clinicopathologic relationship. METHODS: 557 colorectal cancer cases were collected, including 325 colon cancer and 232 rectal cancer. PCR amplification and DNA sequencing were...
Topics
- Adolescent
- Adult
- Aged
- Aged, 80 and over
- Asian People
- Codon
- Colon, Ascending
- Colon, Descending
- Colonic Neoplasms
- Colorectal Neoplasms
- Female
- Humans
- Male
- Middle Aged
- Mutation
- Proto-Oncogene Proteins
- Proto-Oncogene Proteins B-raf
- Proto-Oncogene Proteins p21(ras)