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Article

Impact of genetic heterogeneity in polymerase of hepatitis B virus on dynamics of viral load and hepatitis B progression.

PloS one - 1 Jan 2013

Huang Chi-Jung, Wu Chih-Feng, Lan Chia-Ying, Sung Feng-Yu, Lin Chih-Lin, Liu Chun-Jen, Liu Hsin-Fu, Yu Ming-Whei

Abstract excerpt

OBJECTIVE: The hepatitis B virus (HBV)-polymerase region overlaps pre-S/S genes with high epitope density and plays an essential role in viral replication. We investigated whether genetic variation in the polymerase region determined long-term dynamics of viral load and the risk of hepatitis B pr...

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Share to Carcinoma, Hepatocellular
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 23936156
DOI: 10.1371/journal.pone.0070169
PMCID: PMC3728348

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23936156-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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