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Article

Association of P53 and ATM polymorphisms with risk of radiation-induced pneumonitis in lung cancer patients treated with radiotherapy.

International journal of radiation oncology, biology, physics - 1 Apr 2011

Yang Ming, Zhang Li, Bi Nan, Ji Wei, Tan Wen, Zhao Lujun, Yu Dianke, Wu Chen, Wang Luhua, Lin Dongxin

Abstract excerpt

PURPOSE: Radiation-induced pneumonitis (RP) is the most common dose-limiting complication in lung cancer patients treated with radiotherapy. Accumulating evidence indicates that P53 and the ataxia telangiectasia-mutated protein (ATM)-dependent signaling response cascade play a crucial role in rad...

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Source

Identifiers

PMID: 20729006
DOI: 10.1016/j.ijrobp.2009.12.042

Genes

ATM

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20729006-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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