Article
IL12RB2 gene is associated with the age of type 1 diabetes onset in Croatian family Trios.
PloS one - 1 Jan 2012
Pehlić Marina, Vrkić Dina, Skrabić Veselin, Jerončić Ana, Stipančić Gordana, Urojić Anita Špehar, Marjanac Igor, Jakšić Jasminka, Kačić Zrinka, Boraska Vesna, Zemunik Tatijana
Abstract excerpt
BACKGROUND: Common complex diseases are influenced by both genetic and environmental factors. Many genetic factors overlap between various autoimmune diseases. The aim of the present study is to determine whether four genetic variants known to be risk variants for several autoimmune diseases could be associated with an increased susceptibility to type 1 diabetes mellitus. METHODS AND FINDINGS: We genotyped four...
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