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Study of polymorphisms in 4q27, 10p15, and 22q13 regions in autoantibodies stratified type 1 diabetes patients.

Autoimmunity - 1 Dec 2011

Espino-Paisán Laura, De La Calle Hermenegildo, Fernández-Arquero Miguel, Figueredo M Angeles, De La Concha Emilio G, Urcelay Elena, Santiago Jose Luis

Abstract excerpt

Type 1 diabetes (T1D) is a multifactorial disease mainly associated with the human leukocyte antigen region. Previous studies suggested the association of interleukin-2 (IL2) gene polymorphisms and its alpha- and beta-chain receptor (IL2RA and IL2RB) variants with different autoimmune diseases such as T1D, celiac disease, multiple sclerosis, and rheumatoid arthritis. All T1D studies were conducted in diabetic...

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Identifiers

PMID: 21875375
DOI: 10.3109/08916934.2011.592515

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