Article
Genetic and infectious profiles of Japanese multiple sclerosis patients.
PloS one - 1 Jan 2012
Yoshimura Satoshi, Isobe Noriko, Yonekawa Tomomi, Matsushita Takuya, Masaki Katsuhisa, Sato Shinya, Kawano Yuji, Yamamoto Ken, Kira Jun-ichi
Abstract excerpt
BACKGROUND: Nationwide surveys conducted in Japan over the past thirty years have revealed a four-fold increase in the estimated number of multiple sclerosis (MS) patients, a decrease in the age at onset, and successive increases in patients with conventional MS, which shows an involvement of multiple sites in the central nervous system, including the cerebrum and cerebellum. We aimed to clarify whether genetic...
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