Article
Distinct genetic and infectious profiles in Japanese neuromyelitis optica patients according to anti-aquaporin 4 antibody status.
Journal of neurology, neurosurgery, and psychiatry - 1 Jan 2013
Yoshimura Satoshi, Isobe Noriko, Matsushita Takuya, Yonekawa Tomomi, Masaki Katsuhisa, Sato Shinya, Kawano Yuji, Kira Jun-ichi
Abstract excerpt
OBJECTIVE: To clarify whether genetic and common infectious backgrounds are distinct, according to anti-aquaporin 4 (AQP4) antibody status in Japanese patients with neuromyelitis optica (NMO). METHODS: We analysed human leucocyte antigen (HLA)-DRB1 and HLA-DPB1 alleles, and IgG antibodies against Helicobacter pylori, Chlamydia pneumoniae, varicella zoster virus and Epstein-Barr virus nuclear antigen (EBNA) in 116...
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