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Article

Genomic HLA profiles of MS in Hokkaido, Japan: important role of DPB1*0501 allele.

Journal of neurology - 1 Mar 2000

Fukazawa T, Kikuchi S, Sasaki H, Yabe I, Miyagishi R, Hamada T, Tashiro K

Abstract excerpt

The polymorphism of the HLA class II genes was investigated in 97 patients with multiple sclerosis (MS) in Hokkaido, the northernmost main island of Japan. Of these, 80 patients were classified as having conventional MS and 17 as having opticospinal MS (OS-MS). Our findings confirmed a previous report that the DPB 1*0501 allele is positively associated with OS-MS (P = 0.0043). The frequency of DPB 1*0501 was also...

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Identifiers

PMID: 10787110
DOI: 10.1007/s004150050558

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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