HLA-dPB1*0501 is not uniquely associated with opticospinal multiple sclerosis in Japanese patients. Important role of DPB1*0301.

doi:10.1191/135248506ms1252oa

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

HLA-dPB10501 is not uniquely associated with opticospinal multiple sclerosis in Japanese patients. Important role of DPB10301.

Multiple sclerosis (Houndmills, Basingstoke, England) - 1 Feb 2006

Fukazawa T, Kikuchi S, Miyagishi R, Miyazaki Y, Yabe I, Hamada T, Sasaki H

Abstract excerpt

Apart from its unique lesion distribution pattern, the opticospinal form of multiple sclerosis (OSMS) is distinct among Japanese patients who satisfy the diagnostic criteria of MS. OSMS has been suggested to be strongly associated with HLA-DPB1*0501 in Japanese. However, association of DPB1*0301 with non-OSMS and lack of DPB1*0301 in OSMS were also reported. To verify the role of DPB1*0501 and DPB1*0301 in...

Topics

Adult
Age of Onset
Female
Gene Frequency
HLA-DP Antigens
HLA-DP beta-Chains
Humans
Japan
Male
Middle Aged
Multiple Sclerosis
Phenotype

Source

Open in PubMed

Identifiers

PMID: 16459716
DOI: 10.1191/135248506ms1252oa

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics